PENYIMPANGAN KDM PATOGENESIS GNA/GNK

PENYIMPANGAN KDM PATOGENESIS GNA/GNK

                                                                                Infeksi Bakteri(strep.β hemolitikus)

Timbul lesi

                                                                                Pembentukan kompleks                  F/ ginjal menurun     Eritropoetin    

Rx.radang                                                                antigen-antibody dlm darah

(PMN+trombosit                                                     yang bersirkulasi dlm glome-                       GFR            Eritrosit menurun

tertarik ke arah lesi)                                                  rulus

 

Pelepasan zat pirogen                                               Komplemen akan terfiksasi                  sekresi rennin            Anemia 

                                                                                   Dalam   membran basalis   

Merangsang IL-I                                                                                                                      Mengubah angio-

Mediator kimia lainnya                                             Kebocoran kapiler glomerlus                 tensinogen mjd        Suplai O₂ dan nutrisi

                                                                                                                                                   Angiotensin I          ke sel jaringan ber(-)

  

Meningkatkan set point                                            eritrosit&protein keluar      proteinemia            Angiotensin I mjd    metabolisme me     

                                                                                                                                                                                                                             Angiotensin II      

Vasokontrik,diawali                                                  Hematuria&proteinuria    hipoalbuminemia    oleh enzim ACE           ATP me       

Dgn menggigil                                                                                                                                                                          dalam paru-paru.

                                                                                   Proliferasisel&fibrin        Tek.Osmotik ko-                                                          Kelemahan                  

Pe  Suhu Tubuh

Intolerance Aktivity

                                                                                   Yang terakumulasi           Loid menurun          merangsang kor-

                                                                                   Dlm kapsula Bowmann                          teks adrenal

 

Perubahan status kesehatan                                       Perfusi kapiler glo-          Tekanan hidros-       sekresi aldosteron

                                                                                   merulus menurun              tatik meningkat       meningkat           

§ Me    reabsorbsi tubulus § Retensi Na&air

Kurang informasi                                                               

Kecemasan

                                                                                   Ureum&kreatinin dlm       Edema                                                                    ekskresi  uine (-)

Ggn perfusi jaringan

                                                                                                                                                                                                                                                                       

                                                                                                                             Darah me    

                                                                                                                                                                                            Imobilisasi

Perubahan status nutrisi kurang dari kebutuhan

                                                                                                                   azotemia                                                                                   Vol.plasma              oliguria&anuria        

§ Ggn pola tidur § Resti kerusakan integritas kulit

                                                                                                                             

Kelebihan vol.cairan

                                                             anorexia     rasa mual                       merangsang N.Vagal                                                               Hipertensi